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馃珌 FIB-4 Index

Liver Fibrosis Screening

馃挕 Formula: FIB-4 = (Age 脳 AST) / (Platelet 脳 鈭欰LT)
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FIB-4 Index

📛 Interpretation

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馃挕 Clinical Notes

鈥?Low FIB-4 (<1.30): Strong NPV for advanced fibrosis
鈥?High FIB-4 (>2.67): Strong PPV for advanced fibrosis
鈥?Indeterminate (1.30-2.67): Consider additional testing
鈥?Useful for NAFLD/NASH screening
鈥?Non-invasive alternative to liver biopsy

📚 Evidence & Guidelines Class I Recommendation
★★★★★ (2006)
Citation: Sterling RK, Lissen E, Clumeck N, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology. 2006;43(6):1317-1325.
Guideline: AASLD NAFLD Guidelines
📔 View on PubMed
class="disc">⚠️ Medical Disclaimer

For medical reference only. Use with other clinical data.